Complexities of Protein Therapeutics and Immunogenicity
نویسندگان
چکیده
منابع مشابه
Immunogenicity of protein therapeutics.
Protein therapeutics, such as monoclonal antibodies, enzymes and toxins, hold significant promise for improving human health. However, repeated administration of protein therapeutics, whether natural or recombinant, often leads to the induction of undesirable anti-drug antibodies (ADAs), which interfere with or neutralize the effect of the drug. Although an immune response to foreign proteins c...
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ژورنال
عنوان ژورنال: Journal of Bioanalysis & Biomedicine
سال: 2015
ISSN: 1948-593X
DOI: 10.4172/1948-593x.1000126